Incremental value of 18F-fluorocholine PET/CT in the localization of double parathyroid adenomas

Paul Lalire 1 Sang Ly 2 Sophie Deguelte 3 Martine Patey 4 David Morland 5, 6, 7
1 Unité thyroïde, Institut Jean Godinot, Reims
2 Service d'Endocrinologie-Diabétologie-Nutrition
3 Service de chirurgie digestive et endocrinienne, et Laboratoire d’anatomie et cytologie pathologique, Hôpital Robert Debré, CHU de Reims
4 Laboratoire d’anatomie et cytologie pathologique, Hôpital Robert Debré, CHU de Reims
5 Département de Médecine Nucléaire, Institut Jean Godinot
6 Laboratoire de Biophysique, UFR de Médecine
7 CRESTIC - Centre de Recherche en Sciences et Technologies de l'Information et de la Communication - EA 3804
Abstract : A 73-year-old man displaying primary hyperparathyroidism with severe hypercalcemia (Ca: 4.1 mmol/l, PTH > 600 pmol/l) was referred for preoperative localization of a parathyroid adenoma. 99mTc-pertechnetate and 99mTc-sestaMIBI dual tracer scintigraphy displayed a mild focal uptake in the projection of the right thyroid lobe with negative ultrasonography. 18F-Fluorocholine PET/CT was quickly performed considering this discrepancy and not only confirmed the scintigraphic findings but also revealed a second contralateral focus of increased uptake, both later confirmed by operative consideration (the two other parathyroid glands are considered normal by the surgeon), pathology, and intraoperative parathyroid hormone assessment.
Document type :
Journal articles
Complete list of metadatas
https://hal.univ-reims.fr/hal-01822388
Contributor : Nicolas Passat <>
Submitted on : Monday, June 25, 2018 - 9:25:16 AM
Last modification on : Wednesday, August 29, 2018 - 1:12:01 PM

Identifiers

  • HAL Id : hal-01822388, version 1

Collections

URCA | CRESTIC

Citation

Paul Lalire, Sang Ly, Sophie Deguelte, Martine Patey, David Morland. Incremental value of 18F-fluorocholine PET/CT in the localization of double parathyroid adenomas. Clinical Nuclear Medicine, Lippincott, Williams & Wilkins, 2017, 42 (3), pp.218-220. ⟨hal-01822388⟩

Export

BibTeX TEI DC DCterms EndNote

Share

Metrics

Record views

42

 

HAL-contact@univ-reims.fr