New Antioxidant Flavonoids From The Aerial Parts Of Secamone Afzelii - Université de Reims Champagne-Ardenne Access content directly
Journal Articles Journal of Antioxidant Activity Year : 2016

New Antioxidant Flavonoids From The Aerial Parts Of Secamone Afzelii

Abstract

A bioassay-guided fractionation of petroleum ether, EtOAc and n-BuOH soluble parts of the 80% hydromethanol extract was performed to investigate the antioxidant activity of Secamoneafzeliiaerial parts using DPPH free radical scavenging assay. The results revealed that EtOAc and n-BuOH soluble parts have moderate to good DPPH radical scavenging activity (EC50 = 139.3 and 30.5 μg/mL, respectively). Therefore, from the most active fractions of EtOAc and n-BuOH soluble parts were isolated two new flavonoid diglycosides quercetin-3-O-β-d-apiofuranosyl-(1→2)-α-l-rhamnopyranoside and genkwanin-8-C-β-d-apiofuranosyl-(1→2)-β-d-glucopyranoside in addition to nine known compounds (2-10). Their structures were elucidated on the basis of spectroscopic data including 1D- and 2D-NMR and ESI-MS. The ability of the isolated compounds to scavenge the DPPH was evaluated. The new compound 1, quercitrin (3) and rutin (6) have antioxidant potential with EC50 values ranging from 8.4 to 13.6 µg/mL, compared to the standard ascorbic acid (EC50 7.4 µg/mL).
Fichier principal
Vignette du fichier
New antioxidant flavonoids from the aerial parts of Secamone afzelii.pdf (222.15 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-01834021 , version 1 (05-11-2021)

Identifiers

Cite

Abdulmagid Alabdul Magid, Philomène Akoua Yao-Kouassi, Diane Patricia Apie Gossan, Claire Mairot, Laurence Voutquenne-Nazabadioko. New Antioxidant Flavonoids From The Aerial Parts Of Secamone Afzelii. Journal of Antioxidant Activity, 2016, 1 (2), pp.8 - 16. ⟨10.14302/issn.2471-2140.jaa-15-887⟩. ⟨hal-01834021⟩
61 View
24 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More