Skip to Main content Skip to Navigation
Journal articles

Prophylactic neck dissection for low-risk differentiated thyroid cancers: Risk-benefit analysis

Abstract : Background. The benefit of neck dissection is the subject of debate in differentiated thyroid cancer (DTC). We analyze the risk-benefit of neck dissection for low-risk DTC without detectable lymph nodes. Methods. We conducted a retrospective study from 1983 to 2003; which included 295 patients without detectable lymph nodes who were treated by thyroidectomy with (C1) or without (C-) neck dissection. All patients had iodine131 therapy. We compared the frequency of remission, disease progression, and permanent complications between groups. Results. Two hundred twelve patients comprised the C1 group, and 83 patients the C-group. Respectively for C1 versus C-, remission rates were 92% versus 89.2% (p 5 .40), and progressive disease observed was 3.3% versus 7.2% (p 5 .10). Permanent hypoparathyroidism occurred in 15.1% in C1 versus 3.6% in C-(p 5 .006). Conclusion. The risk-benefit analysis of neck dissection in patients with low-risk DTC shows no benefit in terms of complete remission or occurrence of progression. However, risk of complications seems to be higher in patients with neck dissection.
Document type :
Journal articles
Complete list of metadatas

Cited literature [54 references]  Display  Hide  Download

https://hal.univ-reims.fr/hal-02453755
Contributor : Valerian Dormoy <>
Submitted on : Thursday, June 4, 2020 - 5:51:41 PM
Last modification on : Friday, June 12, 2020 - 3:15:50 AM

File

DubernardXavier_JAMAoto_2016.p...
Publisher files allowed on an open archive

Identifiers

Collections

Citation

Xavier Dubernard, Sandrine Dabakuyo, Samiratou Ouédraogo, Koceila Amroun, David Kere, et al.. Prophylactic neck dissection for low-risk differentiated thyroid cancers: Risk-benefit analysis. Archives of Otorhinolaryngology - Head & Neck Surgery, JAMA Network- American Medical Association, 2016, 38 (7), pp.1091-1096. ⟨10.1002/hed.24402⟩. ⟨hal-02453755⟩

Share

Metrics

Record views

40

Files downloads

23