A new 2-alkylhydroquinone glucoside from Phagnalon saxatile (L.) Cass
Abstract
A new 2-alkylhydroquinone glucoside, 1-O-β-d-glucopyranosyl-1,4-dihydroxy-2-((E) 2-oxo-3-butenyl)benzene (1), in addition to nine known compounds were isolated from the aerial parts of Phagnalon saxatile (L.) Cass. (Asteraceae). Their structures were identified based on spectroscopic methods including 1D and 2D NMR, mass spectrometry (HR-ESI-MS), UV spectral analyses and by comparison with literature data. The cytotoxic activity of three isolated compounds (1-3) was evaluated against fibrosarcoma (HT1080), human lung cancer (A549) and breast cancer (MCF7) cell lines.
Domains
Physics [physics] Physics [physics] Biological Physics [physics.bio-ph] Life Sciences [q-bio] Biochemistry, Molecular Biology Biophysics Life Sciences [q-bio] Cellular Biology Subcellular Processes [q-bio.SC] Life Sciences [q-bio] Cancer Engineering Sciences [physics] Optics / Photonic Engineering Sciences [physics] Signal and Image processing Life Sciences [q-bio] Cellular Biology Cell Behavior [q-bio.CB]
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