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A new 2-alkylhydroquinone glucoside from Phagnalon saxatile (L.) Cass

Abstract : A new 2-alkylhydroquinone glucoside, 1-O-β-d-glucopyranosyl-1,4-dihydroxy-2-((E) 2-oxo-3-butenyl)benzene (1), in addition to nine known compounds were isolated from the aerial parts of Phagnalon saxatile (L.) Cass. (Asteraceae). Their structures were identified based on spectroscopic methods including 1D and 2D NMR, mass spectrometry (HR-ESI-MS), UV spectral analyses and by comparison with literature data. The cytotoxic activity of three isolated compounds (1-3) was evaluated against fibrosarcoma (HT1080), human lung cancer (A549) and breast cancer (MCF7) cell lines.
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Submitted on : Thursday, September 3, 2020 - 11:34:39 AM
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Hanene Cherchar, Meriem Lehbili, Djemaa Berrehal, Hamid Morjani, Abdulmagid Alabdul Magid, et al.. A new 2-alkylhydroquinone glucoside from Phagnalon saxatile (L.) Cass. Natural Product Research, Taylor & Francis, 2018, 32 (9), pp.1010-1016. ⟨10.1080/14786419.2017.1375918⟩. ⟨hal-02929189⟩



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