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Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial

Tim Harrison Borja Cosio Annie Burden Lawrence Mcdermott Esther Garcia Gil James Zangrilli Wolfgang Pohl Robert Voves Maud Deschampheleire Renaud Louis Jean-Benoit Martinot Rudi Peché Kenneth Chapman Amarjit Cheema Delbert Dorscheid J. Mark Fitzgerald Remi Gagnon William Patrick Killorn Ronald Olivenstein George Philteos Clare Ramsey J. Douglass Rolf Brandie Walker Ole Hilberg Tina Skjold Ingrid Titlestad Auli Hakulinen Maritta Kilpeläinen Michèle Ben Hayoun Philippe Bonniaud Arnaud Bourdin 1, 2 Pascal Chanez Frédéric de Blay Gaëtan Deslee 3 Gilles Devouassoux Alain Didier Youcef Douadi Stéphanie Fry Gilles Garcia Pierre-Olivier Girodet Christophe Leroyer Antoine Magnan Guillaume Mahay Cécilia Nocent Christophe Pison Pauline-Marie Roux Camille Taillé Juliana-Angelica Tiotiu Ekkehard Beck Margret Jandl Christian Kaehler Frank Kässner Frank Koesters Juliane Kronsbein Thomas Schaum Christian Schulz Dirk Skowasch Christian Taube Tobias Welte Andrés de Roux Bianca Beghé Francesco Blasi Giorgio Walter Canonica Giovanna Carpagnano Cristiano Caruso Angelo Guido Corsico Elio Constantino Nunzio Crimi Piero Maestrelli Francesco Menzella Manlio Milanese Alberto Papi Girolamo Pelaia Laura Pini Pierachille Santus Eleonora Savi Nicola Scichilone Gianenrico Senna Giuseppe Spadaro Adriano Vaghi Steven Gans Jurgen Hölters B. Langeveld Willem Pieters G.H.A. Staaks Ilonka van Veen J.W.K. van den Berg Gunnar Einvik Sverre Lehmann Ismael Ali García Carlos Almonacid Irina Bobolea Paloma Campo Mozo Gustavo de Luiz Christian Domingo Ribas José María Echave-Sustaeta María-Tomé Juan Luis García Rivero Borja García-Cosío Piqueras Ana Gómez-Bastero Fernández Ruperto González Pérez Aythamy Henríquez Santa Carlos Martínez Rivera Xavier Muñoz Gall Jacinto Ramos Jose Gregorio Soto Campos Carmen Vidal Pan Nikolai Stenfors Alf Tunsäter Ines Vinge Rekha Chaudhuri Timothy Harrison Adel Mansur Shuaib Nasser Monica Nordstrom Paul Pfeffer Dinesh Saralaya Philip Short Arun Adlakha Oral Alpan Francis Averill Anil Badhwar Jose Bardelas Barbara Baxter George Bensch William Berger Jonathan Bernstein Tracy Bridges Ryan Brimeyer William Calhoun Edward Campbell William Brett Cherry Geoffrey Chupp Lee Clore John Cohn Jeremy Cole John Condemi James Cury Benjamin Davis Samuel Deleon Luis Delacruz Joseph Diaz David Erb Emeka Eziri Faisal Fakih Douglas Fiedler David Fost Stephen Fritz Erika Gonzalez Brad Goodman Peter Gottlieb Gregory Gottschlich Richard Gower Rizan Hajal James Harris Hengameh Heidarian-Raissy Albrecht Heyder David Hill Fernando Holguin Iftikhar Hussain Jonathan Illowite Joshua Jacobs Mikell Jarratt Harold Kaiser Neil Kao Ravindra Kashyap David Kaufman Edward Kent Kenneth Kim Ryan Klein Monica Kraft Ritsu Kono Shahrukh Kureishy Jeffrey Leflein Mila Leong Huamin Li Robert Lin Njira Lugogo Michael Marcus Diego Jose Maselli Caceres Vinay Mehta Curtis Mello Mark Millard Aaron Milstone Arjun Mohan Wendy Moore Mark Moss Nayla Mumneh Thomas O'Brien David Ostransky Michael Palumbo Purvi Parikh Sudhir Parikh Amit Patel Guido Perez Warren Pleskow Bruce Prenner Dileep Puppala John Ramey Joan Reibman Ramon Reyes Emory Robinette Ileana Rodicio Stephen Ryan Sudhir Sekhsaria Barry Sigal Vinay Sikand Weily Soong Selwyn Spangenthal Roy St. John Gary Steven Vijay Subramaniam Kaharu Sumino Eric Sztejman Ricardo Tan Tonny Tanus Charles Thompson Carl Thornblade Manuel Villareal Sally Wenzel Heidi Zafra Tomasz Ziedalski
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https://hal.univ-reims.fr/hal-03170335
Contributor : Valerian Dormoy <>
Submitted on : Tuesday, March 16, 2021 - 10:15:53 AM
Last modification on : Tuesday, March 23, 2021 - 3:31:58 AM

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Tim Harrison, Borja Cosio, Annie Burden, Lawrence Mcdermott, Esther Garcia Gil, et al.. Onset of effect and impact on health-related quality of life, exacerbation rate, lung function, and nasal polyposis symptoms for patients with severe eosinophilic asthma treated with benralizumab (ANDHI): a randomised, controlled, phase 3b trial. The Lancet Respiratory Medicine, Elsevier, 2021, 9 (3), pp.260-274. ⟨10.1016/S2213-2600(20)30414-8⟩. ⟨hal-03170335⟩

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