Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues - Université de Reims Champagne-Ardenne Access content directly
Journal Articles Emerging Infectious Diseases Year : 2016

Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues

Alexis Bouin
  • Function : Author
Yohan Nguyen
  • Function : Author
Laboratoire de Virologie Médicale et Moléculaire - EA 4684
Michel Wehbe
  • Function : Author
Fanny Renois
  • Function : Author
Paul Fornes
  • Function : Author
Firouze Bani-Sadr
  • Function : Author
Damien Metz
  • Function : Author
Laurent Andreoletti

Abstract

We performed deep sequencing analysis of the enterovirus 5′ noncoding region in cardiac biopsies from a patient with dilated cardiomyopathy. Results displayed a mix of deleted and full-length coxsackievirus B3, characterized by a low viral RNA load (8.10 2 copies/µg of nucleic acids) and a low viral RNA positive-sense to RNA negative-sense ratio of 4.8.

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Life Sciences [q-bio]
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https://hal.science/hal-03267024

Submitted on : Tuesday, June 22, 2021-11:55:04 AM

Last modification on : Thursday, May 18, 2023-3:55:53 AM

Long-term archiving on: Thursday, September 23, 2021-6:24:07 PM

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hal-03267024 , version 1 (22-06-2021)

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Alexis Bouin, Yohan Nguyen, Michel Wehbe, Fanny Renois, Paul Fornes, et al.. Major Persistent 5′ Terminally Deleted Coxsackievirus B3 Populations in Human Endomyocardial Tissues. Emerging Infectious Diseases, 2016, 22, pp.1488 - 1490. ⟨10.3201/eid2208.160186⟩. ⟨hal-03267024⟩

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