Triterpenoid saponins from Scabiosa stellata collected in North-eastern Algeria - Université de Reims Champagne-Ardenne Access content directly
Journal Articles Phytochemistry Year : 2018

Triterpenoid saponins from Scabiosa stellata collected in North-eastern Algeria

Abstract

Eight undescribed triterpenoid saponins, scabiostellatosides A-H, together with three known compounds were isolated from the whole plant of Scabiosa stellata L. Their structures were established by spectroscopic analyses (1D, 2D-NMR and HRESIMS) and chemical methods. Scabiostellatosides A-H were evaluated for their cytotoxicity against human fibrosarcoma cell line (HT1080). Scabiostellatoside F, a heptasaccharide derivative of oleanolic acid, exhibited moderate cytotoxicity against HT1080 cell line with IC50 value of 12.0 μM.
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Dates and versions

hal-03351420 , version 1 (22-09-2021)

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Meryem Lehbili, Abdulmagid Alabdul Magid, Ahmed Kabouche, Laurence Voutquenne-Nazabadioko, Hamid Morjani, et al.. Triterpenoid saponins from Scabiosa stellata collected in North-eastern Algeria. Phytochemistry, 2018, 150, pp.40-49. ⟨10.1016/j.phytochem.2018.03.005⟩. ⟨hal-03351420⟩
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