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Large International Validation of ABSIS and PDAI Pemphigus Severity Scores

Abstract : (ABSIS) scores have been proposed to provide an objective measure of pemphigus activity. These scores have been evaluated only on already treated patients mainly with mild to moderate activity. The objective was to assess the interrater reliability of ABSIS and PDAI scores and their correlation with other severity markers in a large international study. Consecutive patients with newly diagnosed pemphigus were enrolled in 31 centers. Severity scores were recorded during a 24-month period by the same two blinded investigators. Serum was collected at each visit for ELISA measurement of anti-desmoglein antibodies. The intraclass correlation coefficient (ICC) and Spearman rank correlation coefficient were calculated. A total of 116 patients with pemphigus vulgaris (n ¼ 84) or pemphigus foliaceus (n ¼ 32) were
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Submitted on : Friday, November 19, 2021 - 4:06:09 PM
Last modification on : Tuesday, December 7, 2021 - 3:16:59 AM
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Vivien Hébert, Claire Boulard, Estelle Houivet, Sophie Lehembre, Luca Borradori, et al.. Large International Validation of ABSIS and PDAI Pemphigus Severity Scores. Journal of Investigative Dermatology, Nature Publishing Group, 2019, 139 (1), pp.31-37. ⟨10.1016/j.jid.2018.04.042⟩. ⟨hal-03436997⟩



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