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Journal Articles Journal of Investigative Dermatology Year : 2019

Large International Validation of ABSIS and PDAI Pemphigus Severity Scores

Vivien Hébert
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Claire Boulard
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Estelle Houivet
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Sophie Duvert Lehembre
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Luca Borradori
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Rocco Della
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Claudio Feliciani
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Luca Fania
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Giovanna Zambruno
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Diana B Camaioni
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Biago Didona
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Branka Marinovic
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Enno Schmidt
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Nina Schumacher
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Christian Hü Nefeld 10
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Stefan Schanz
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Johannes Steffen Kern
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Silke Hofmann
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Anne Charlotte Bouyeure
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Catherine Picard-Dahan
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Catherine Prost-Squarcioni
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Frederic Caux
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Marina Alexandre
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Saskia Ingen-Housz-Oro
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Martine Bagot
Emmanuelle Tancrede-Bohin
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Jean David Bouaziz
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Nathalie Franck
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Pierre Vabres
Bruno Labeille
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Marie Aleth Richard
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Emmanuel Delaporte
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Alain Dupuy
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Michel d'Incan
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Gaelle Quereux
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François Skowro
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Cristina Bulai Livideanu
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Marie Beylot-Barry
Marie Sylvie Doutre
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Martine Avenel-Audran
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Christophe Bedane
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Laurent Machet
Hervé Maillard
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Denis Jullien
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Sebastien Debarbieux
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Bruno Sassolas
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Laurent Misery
Claire Abasq
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Olivier Dereure
Philippe Lagoutte
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Vincent Ferranti
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Victoria P Werth
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Dedee F Murrell
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Michael Hertl
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Jacques Benichou
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Pascal Joly
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Sophie Duvert Lehembre
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Rocco Della Torre
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Christian Hünefeld
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Johannes Steffen Kern
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Anne Charlotte Bouyeure
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Jean David Bouaziz
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Marie Aleth Richard
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Michel D’incan
Cristina Bulai Livideanu
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Marie Sylvie Doutre
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Abstract

(ABSIS) scores have been proposed to provide an objective measure of pemphigus activity. These scores have been evaluated only on already treated patients mainly with mild to moderate activity. The objective was to assess the interrater reliability of ABSIS and PDAI scores and their correlation with other severity markers in a large international study. Consecutive patients with newly diagnosed pemphigus were enrolled in 31 centers. Severity scores were recorded during a 24-month period by the same two blinded investigators. Serum was collected at each visit for ELISA measurement of anti-desmoglein antibodies. The intraclass correlation coefficient (ICC) and Spearman rank correlation coefficient were calculated. A total of 116 patients with pemphigus vulgaris (n ¼ 84) or pemphigus foliaceus (n ¼ 32) were
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Dates and versions

hal-03436997 , version 1 (19-11-2021)

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Vivien Hébert, Claire Boulard, Estelle Houivet, Sophie Duvert Lehembre, Luca Borradori, et al.. Large International Validation of ABSIS and PDAI Pemphigus Severity Scores. Journal of Investigative Dermatology, 2019, 139 (1), pp.31-37. ⟨10.1016/j.jid.2018.04.042⟩. ⟨hal-03436997⟩
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