Therapeutic bronchoscopy for malignant central airway obstruction: Introduction to the EpiGETIF registry - Université de Reims Champagne-Ardenne Access content directly
Journal Articles Respirology Year : 2024

Therapeutic bronchoscopy for malignant central airway obstruction: Introduction to the EpiGETIF registry

Nicolas Guibert
Pascalin Roy
  • Function : Author
Lyria Amari
  • Function : Author
Julien Legodec
  • Function : Author
Bruno Escarguel
  • Function : Author
Clément Fournier
  • Function : Author
Frederic Wallyn
  • Function : Author
Laurent Cellerin
  • Function : Author
Christine Lorut
  • Function : Author
Daniela Usturoi
  • Function : Author
Thomas Egenod
  • Function : Author
Nicolas Favrolt
  • Function : Author
Pascal Schlossmacher
  • Function : Author
Valerian Bourinet
  • Function : Author
Perrot Loïc
Samy Lachkar
Juliette Camuset
  • Function : Author
Amandine Briault
  • Function : Author
Romain Kessler
  • Function : Author
Christophe Gut-Gobert
  • Function : Author
Gilles Mangiapan
  • Function : Author
Nicolas Carnot
  • Function : Author
Eric Briens
  • Function : Author
Adrian Crutu
  • Function : Author
Armelle Marceau
  • Function : Author
Bénédicte Toublanc
  • Function : Author
Maxime Dewolf
  • Function : Author
Julien Dutilh
  • Function : Author
Julie Tronchetti
  • Function : Author
Philippe Astoul
  • Function : Author
Jean‐michel Vergnon
  • Function : Author
Hervé Dutau
  • Function : Author

Abstract

Abstract Background and Objective EpiGETIF is a web‐based, multicentre clinical database created in 2019 aiming for prospective collection of data regarding therapeutic rigid bronchoscopy (TB) for malignant central airway obstruction (MCAO). Methods Patients were enrolled into the registry from January 2019 to November 2022. Data were prospectively entered through a web‐interface, using standardized definitions for each item. The objective of this first extraction of data was to describe the population and the techniques used among the included centres to target, facilitate and encourage further studies in TB. Results Overall, 2118 patients from 36 centres were included. Patients were on average 63.7 years old, mostly male and smokers. Most patients had a WHO score ≤2 (70.2%) and 39.6% required preoperative oxygen support, including mechanical ventilation in 6.7%. 62.4% had an already known histologic diagnosis but only 46.3% had received any oncologic treatment. Most tumours were bronchogenic (60.6%), causing mainly intrinsic or mixed obstruction (43.3% and 41.5%, respectively). Mechanical debulking was the most frequent technique (67.3%), while laser (9.8%) and cryo‐recanalization (2.7%) use depended on local expertise. Stenting was required in 54.7%, silicone being the main type of stent used (55.3%). 96.3% of procedure results were considered at least partially successful, resulting in a mean 4.1 points decrease on the Borg scale of dyspnoea. Complications were noted in 10.9%. Conclusion This study exposes a high volume of TB that could represent a good source of future studies given the dismal amount of data about the effects of TB in certain populations and situations.
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Dates and versions

hal-04502123 , version 1 (13-03-2024)

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Nicolas Guibert, Pascalin Roy, Lyria Amari, Julien Legodec, Bruno Escarguel, et al.. Therapeutic bronchoscopy for malignant central airway obstruction: Introduction to the EpiGETIF registry. Respirology, 2024, ⟨10.1111/resp.14697⟩. ⟨hal-04502123⟩

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