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Temporal uptake patterns of 18F-fluorocholine among hyperfunctioning parathyroid glands

Abstract : Optimal scan time of 18F-fluorocholine (FCH) PET/CT for localization of hyperfunctioning parathyroid glands is poorly documented. We report a small series of 9 histologically proven hyperfunctioning parathyroid gland with heterogeneous temporal uptake profile. Thirty-minute dynamic acquisition starting just after 18F-fluorocholine administration and delayed acquisition were recorded. Three different uptake patterns are seen (early washout, stable uptake, late increase) indicating the importance of an early (5–10 minutes) acquisition. A late acquisition (60 minutes) could be useful when the early acquisition is negative. No correlations were noted between uptake profile and histological or genetic results.
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https://hal.univ-reims.fr/hal-01822373
Contributor : Nicolas Passat <>
Submitted on : Monday, June 25, 2018 - 9:01:47 AM
Last modification on : Saturday, April 4, 2020 - 4:26:38 PM

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David Morland, Capucine Richard, François Godard, Sophie Deguelte, Brigitte Delemer. Temporal uptake patterns of 18F-fluorocholine among hyperfunctioning parathyroid glands. Clinical Nuclear Medicine, Lippincott, Williams & Wilkins, 2018, 43 (7), pp.504-505. ⟨10.1097/RLU.0000000000002132⟩. ⟨hal-01822373⟩

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