Temporal uptake patterns of 18F-fluorocholine among hyperfunctioning parathyroid glands - Archive ouverte HAL Access content directly
Journal Articles Clinical Nuclear Medicine Year : 2018

Temporal uptake patterns of 18F-fluorocholine among hyperfunctioning parathyroid glands

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Abstract

Optimal scan time of 18F-fluorocholine (FCH) PET/CT for localization of hyperfunctioning parathyroid glands is poorly documented. We report a small series of 9 histologically proven hyperfunctioning parathyroid gland with heterogeneous temporal uptake profile. Thirty-minute dynamic acquisition starting just after 18F-fluorocholine administration and delayed acquisition were recorded. Three different uptake patterns are seen (early washout, stable uptake, late increase) indicating the importance of an early (5–10 minutes) acquisition. A late acquisition (60 minutes) could be useful when the early acquisition is negative. No correlations were noted between uptake profile and histological or genetic results.
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Dates and versions

hal-01822373 , version 1 (25-06-2018)

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David Morland, Capucine Richard, François Godard, Sophie Deguelte, Brigitte Delemer. Temporal uptake patterns of 18F-fluorocholine among hyperfunctioning parathyroid glands. Clinical Nuclear Medicine, 2018, 43 (7), pp.504-505. ⟨10.1097/RLU.0000000000002132⟩. ⟨hal-01822373⟩

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