Temporal uptake patterns of 18F-fluorocholine among hyperfunctioning parathyroid glands.

David Morland 1, 2, 3 Capucine Richard 4 François Godard 1 Sophie Deguelte 5 Brigitte Delemer 6
1 Département de Médecine Nucléaire, Institut Jean Godinot
2 Laboratoire de Biophysique, UFR de Médecine
3 CRESTIC - Centre de Recherche en Sciences et Technologies de l'Information et de la Communication - EA 3804
4 Unité Thyroïde, Institut Jean Godinot
5 Service de Chirurgie Viscérale et Endocrinienne, Hôpital Universitaire Robert Debré
6 Service d'Endocrinologie - Diabète - Nutrition [Reims]
Abstract : Optimal scan time of 18F-fluorocholine (FCH) PET/CT for localization of hyperfunctioning parathyroid glands is poorly documented. We report a small series of 9 histologically proven hyperfunctioning parathyroid gland with heterogeneous temporal uptake profile. Thirty-minute dynamic acquisition starting just after 18F-fluorocholine administration and delayed acquisition were recorded. Three different uptake patterns are seen (early washout, stable uptake, late increase) indicating the importance of an early (5–10 minutes) acquisition. A late acquisition (60 minutes) could be useful when the early acquisition is negative. No correlations were noted between uptake profile and histological or genetic results.
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https://hal.univ-reims.fr/hal-01822373
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Submitted on : Monday, June 25, 2018 - 9:01:47 AM
Last modification on : Wednesday, August 29, 2018 - 1:12:01 PM

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David Morland, Capucine Richard, François Godard, Sophie Deguelte, Brigitte Delemer. Temporal uptake patterns of 18F-fluorocholine among hyperfunctioning parathyroid glands.. Clinical Nuclear Medicine, Lippincott, Williams & Wilkins, 2018, 43 (7), pp.504-505. ⟨hal-01822373⟩

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