Triterpene glycosides from the aerial parts of Gouania longipetala - Archive ouverte HAL Access content directly
Journal Articles Phytochemistry Year : 2017

Triterpene glycosides from the aerial parts of Gouania longipetala

(1) , (1) , (2) , (2) , (3) , (3) , (4) , (1)
1
2
3
4

Abstract

Six previously undescribed triterpenoid saponins, gouaniaside I-VI, were isolated from the aerial parts of Gouania longipetala Hemsl. (Rhamnaceae), in addition to four known triterpenes. The structure elucidation of these compounds was based on analyses of spectroscopic data including 1D- and 2D-NMR and HR-ESI-MS techniques. The inhibitory activity of isolated compounds against promyelocytic leukemia HL60 and human erythromyeloblastoid leukemia K562 cell lines was evaluated and jujuboside I exhibited moderate cytotoxicity, with IC50 values of 13.5 and 21.0 μM, respectively. Among the isolated triterpenes, alphitolic acid exhibited moderate antibacterial activity against Staphylococcus aureus, Enterococcus faecalis and Escherichia coli (MICs 32, 64 and 128 μg/mL, respectively).
Fichier principal
Vignette du fichier
Triterpene glycosides from the aerial parts of Gouania longipetala.pdf (545.56 Ko) Télécharger le fichier
Origin : Files produced by the author(s)

Dates and versions

hal-01834083 , version 1 (05-11-2021)

Identifiers

Cite

Diane Patricia Apie Gossan, Abdulmagid Alabdul Magid, Philomène Akoua Yao-Kouassi, Antoine Ahibo Coffy, Jérôme Josse, et al.. Triterpene glycosides from the aerial parts of Gouania longipetala. Phytochemistry, 2017, 134, pp.71 - 77. ⟨10.1016/j.phytochem.2016.11.004⟩. ⟨hal-01834083⟩
64 View
42 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More